Structure and stability of nucleic acid double helices by molecular dynamics simulations
Speaker
: Prof. Dhananjay Bhattacharyya,
Saha Institute of Nuclear Physics, Kolkata
Saha Institute of Nuclear Physics, Kolkata
Date
: Friday, May 15, 2015
Time
: 11:30 AM
Venue
: Fermion (LH-3)
Title
: Structure and stability of nucleic acid double helices by molecular dynamics simulations
Abstract: In this lecture I would like to emphasize importance of consideration of DNA
polymer of near infinite length to understand its real properties, such as melting bubble formation
leading to cooperative unfolding. I would also discuss features of double helices in different non-
coding and functional RNA molecules, which are of very short length. The importance of different
capping mechanism in stabilization of these short double helices in RNA would be discussed.